Background: Topical corticosteroids (TCs) are widely used for dermatologic diseases.Unfortunately, there exists many adverse effects (local and systemic).These adverse effects are comparable to those observed when glucocorticoids are administered systemically, but they are typically less severe.Aim: To assess the systemic adverse effects of topical
Immune checkpoint inhibitors have revolutionized cancer treatment by enhancing anti-tumor immune responses.However, their impact on fertility is an visceratuant emerging concern, particularly among young patients, including children.This review aims to assess the effects of immune checkpoint inhibitors on reproductive health and fertility preservat
Abstract Background Management of nasal valve collapse (NVC) in patients with a septal deviation can be challenging.Our objective was to determine the opinions of Canadian Otolaryngologists regarding the diagnosis and management of nasal obstruction in patients with septal deviation and NVC.Methods A twenty-question survey was developed for the pur
Objective Immunotherapy has not yielded satisfactory therapeutic responses tinsupe in gastric cancer (GC).However, targeting myeloid checkpoints holds promise for expanding the potential of immunotherapy.This study aims to evaluate the critical role of Siglec-10+ tumor-associated macrophages (TAMs) in regulating antitumor immunity and to explore th